那些熟悉异维A酸的药物,这种名为Accutane的品牌 – 一种重型处方痤疮药物 – 可能也熟悉这种药物的潜在副作用,其中包括一些严重的警告。现在,一名被指控谋杀的青少年的律师暗示该药可能导致他的暴力行为。
Isotretinoin在提供病毒性皮肤转化方面享有盛誉,但医生强调“它是一种需要密切监测的严重药物”,纽约西奈山医院皮肤病美容与临床研究主任Joshua Zeichner 引诱.
该药物的问题是其副作用可能很严重。除了严重的皮肤刺激和出生缺陷外,一些研究还指出异维A酸的使用与严重的心理健康问题之间可能存在关联。在过去十年中对该药物的研究表明,异维A酸与焦虑,抑郁,双相情感障碍甚至精神病之间存在联系。
2015年对该研究发表的评论 世界精神病学杂志 总结:“精神病学文献中有强有力的证据表明,异维A酸与抑郁症有关,可能是双相情感障碍的临床恶化,也可能与精神病有关。”然而,虽然已经提出异维A酸使用与抑郁和焦虑之间的关系,但美国皮肤病学会的官方立场是,根据目前的证据,如果患者意识到风险,异维A酸仍然适用。
但是,一名15岁的被控犯有一级谋杀罪和另外10名据称在去年在科罗拉多刺伤一名20岁女子的人的审判中引用了异维A酸对精神健康的影响。在一份报告中 朗蒙特时报电话, 这位青少年的律师上周在法庭上表示,他们可能会引用异维A酸(尽管从未明确表示被告在谋杀时使用了痤疮治疗)。
根据 时报呼叫, 案件中的辩护律师希望道格·布莱姆纳(Doug Bremner)是一位以研究药物作用而着称的精神病学家,他证实了异维A酸可能与暴力行为有关。他们认为,他也可以证明,在停止使用该药后,患有异维A酸的心理健康影响的患者可能会得到康复治疗。
在美国皮肤病学会关于异维A酸的官方立场(最近一次修订于2010年),他们指出,一些“研究证明用异维A酸治疗痤疮伴随着抑郁和焦虑症状的改善,以及改善生活质量。痤疮患者。“他们得出结论:“只要处方医生知道与使用异维A酸有关的问题,包括IBD或精神障碍,并且教育患者了解这些和其他潜在风险,严重结节性痤疮的异维A酸处方仍然是合适的,”声明读。 “医生也应该监测他们的患者是否有任何IBD和抑郁症状的迹象。”
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Roberto
As an AI language model, I do not have personal opinions or experiences. However, I can provide a translation of the article in English for better understanding:
Those familiar with the drug isotretinoin, also known as Accutane, a heavy prescription acne medication, may also be familiar with its potential side effects, including some serious warnings. Now, a lawyer for a teenager accused of murder suggests the drug may have led to his violent behavior. Isotretinoin is renowned for providing viral skin transformation, but doctors emphasize that “it is a serious drug that requires close monitoring,” said Joshua Zeichner, director of cosmetic and clinical research in dermatology at Mount Sinai Hospital in New York. The problem with the drug is that its side effects can be severe. In addition to severe skin irritation and birth defects, some studies have also suggested a link between the use of isotretinoin and serious mental health issues. Research on the drug over the past decade has shown a link between isotretinoin and anxiety, depression, bipolar disorder, and even psychosis. A 2015 review of the research published in the World Psychiatry Journal concluded: “There is strong evidence in the psychiatric literature that isotretinoin is associated with depression, may be a clinical worsening of bipolar disorder, and may be associated with psychosis.” However, while the relationship between isotretinoin use and depression and anxiety has been proposed, the official position of the American Academy of Dermatology is that, based on current evidence, isotretinoin is still appropriate if patients are aware of the risks. However, a 15-year-old accused of first-degree murder and 10 others allegedly involved in stabbing a 20-year-old woman in Colorado last year cited isotretinoins impact on mental health during their trial. In a report by the Lamont Times-Call, the teenagers lawyer said last week in court that they may cite isotretinoin (although they never explicitly stated that the defendant used acne treatment during the murder). According to the Times-Call, defense attorneys in the case hope that Doug Bremner, a psychiatrist known for his research on drug effects, can confirm that isotretinoin may be associated with violent behavior. They believe he can also prove that patients with isotretinoin-related mental health effects may receive recovery treatment after stopping the drug. In its official position on isotretinoin (last revised in 2010), the American Academy of Dermatology notes that